Best Nightclubs near Route 66 Sign

Discover the perfect blend of dining and entertainment at The Boom Boom Room in St. Louis, offering an unforgettable dinner theater experience.

Dive into St. Louis' vibrant nightlife at Europe Night Club, where electrifying music and dancing await every weekend.

Experience the vibrant nightlife of Dos Salas in Downtown St. Louis, a perfect blend of nightclub, lounge, and bar for unforgettable evenings.

Experience the vibrant nightlife of St. Louis at The Pepper Lounge, your go-to destination for cocktails, dancing, and unforgettable events!

Discover Carson's Sports Bar & Restaurant in Soulard, St. Louis – where sports, karaoke, and delicious bites come together in a lively atmosphere.

Experience the vibrant nightlife and live music at Historic Crossroads, a bar in Soulard, St. Louis, where local culture thrives.

Dive into the electrifying nightlife of St. Louis at Sit & Sip, where music, dance, and cocktails blend for an unforgettable evening.

Discover The Hi-Hat: A charming bar in Soulard, St. Louis, famous for its unique ambiance and diverse drink selection, perfect for nightlife enthusiasts.

Dive into the lively atmosphere at Bastille, St. Louis' premier gay bar, where fun, drinks, and community come together for an unforgettable night.

Discover the vibrant Upper Level Restaurant & Lounge in St. Louis, where culinary delights meet an energetic nightlife experience.

Experience the vibrant nightlife at Big Daddy's Bar in Soulard, where delicious grill cuisine meets lively entertainment in St. Louis.

Experience the vibrant atmosphere and affordable drinks at Cat's Meow, Inc in Soulard, St. Louis, a must-visit bar for tourists seeking local culture.

Discover the perfect blend of art and mixology at Sophie's Artist Lounge in St. Louis, where every cocktail tells a story.

Immerse yourself in the rhythm of St. Louis at Jazz St. Louis, where live music and delicious American cuisine unite in a vibrant atmosphere.

Discover The Dark Room at The Grandel, a lively bar and live music venue in St. Louis offering delicious food, cocktails, and captivating performances.

Discover the lively Venice Café, a vibrant night club and live music venue in St. Louis, perfect for an unforgettable night out.

Discover the energetic nightlife at Da City Nightclub in St. Louis, where music and dance create unforgettable memories.

Experience the vibrant atmosphere and creative cocktails at Ruby's, the premier lounge in Wood River, Illinois.

Experience the lively atmosphere of Rehab Bar And Grill in St. Louis, offering delicious food, karaoke fun, and affordable prices for an unforgettable outing.

Experience the vibrant nightlife at Just John Club, St. Louis' top destination for karaoke, dancing, and inclusive fun!

Discover HandleBar, a lively bar and restaurant in St. Louis, offering delicious food, refreshing drinks, and an energetic dance atmosphere.

Discover the electrifying nightlife of The Grove Area in St. Louis, where vibrant bars and nightclubs create unforgettable experiences.

Experience the vibrant energy of The Get Down in St. Louis, where Italian cuisine meets live music and expertly crafted cocktails.

Discover the pulse of St. Louis nightlife at Club Viva, where dancing, drinks, and good times await every night.

Discover the unique cocktails and charming ambiance of Lazy Tiger, a top cocktail bar in St. Louis's Central West End.

Discover Rosie's Place in St. Louis, a vibrant bar offering craft cocktails, local beers, and a lively atmosphere perfect for unwinding and socializing.

Discover the elegance of AC Lounge, a premier cocktail bar in St. Louis's Central West End, offering crafted cocktails in a chic atmosphere.

Experience the vibrant nightlife at Prism, St. Louis' premier gay bar, known for its inclusive atmosphere and exciting themed events.

Discover the vibrant nightlife of La Onda, a premier night club in The Hill, St. Louis, where music and dance come alive in a lively atmosphere.

El Volcan Discoteque: A vibrant disco club in St. Louis offering unforgettable nights of music, dance, and celebration at the heart of nightlife.

Experience the joy of karaoke at The W Karaoke Lounge in Delmar Loop, where every night is a celebration of music and laughter.

Discover the ultimate nightlife experience at Rise at 300, where vibrant music and a lively atmosphere await you in Alton, Illinois.

Experience the vibrant nightlife at Bubby & Sissy's, where music, dance, and community come together for an unforgettable evening.

Discover the lively nightlife at Pete's Lounge in Godfrey, Illinois, where friendly vibes and great drinks await.

Unleash your nightlife spirit at RYSE Nightclub, where electrifying music and vibrant ambiance create unforgettable moments in St. Charles, Missouri.

Discover the vibrant nightlife at Kubrick's, a lively bar in St. Charles, Missouri, offering an extensive drink menu and a welcoming atmosphere.

Discover the lively nightlife and vibrant music scene at Main Street Honky Tonk in St. Charles, MO - a premier bar for unforgettable experiences.

Experience the lively nightlife at Tuners on Main Street, St. Charles' top night club and bar with exciting entertainment and delicious drinks.

Discover the vibrant culinary scene and lively nightlife at Quintessential Dining & Nightlife in St. Charles, where every meal is an experience.

Discover the vibrant nightlife at The Moonshine Blues Bar in St. Charles, where live blues music and delightful drinks create an unforgettable experience.

Experience vibrant dining at Bar Louie in St. Charles, where delicious food meets a lively atmosphere, perfect for tourists seeking fun and flavor.

Experience the lively atmosphere of The Corner Bar in St. Charles, a dive bar perfect for socializing and enjoying local brews.

Discover the lively atmosphere and affordable drinks at Drinking Horn, a popular bar in St. Charles, MO, perfect for socializing and unwinding.

Discover Traffic Jam, St. Charles' premier cocktail bar, where crafted drinks meet a vibrant atmosphere for an unforgettable night out.

Discover the lively nightlife at Hot Spot, a must-visit night club in High Ridge, Missouri, offering great music, affordable drinks, and an unforgettable atmosphere.

Discover the vibrant nightlife at The JA & MA Dark Church & Hookah Lounge in Kane, where exotic hookah meets an energetic club scene.