Background

106 Main, Research Triangle Travel Guide

4.6 (217)

Discover the vibrant nightlife of Durham at 106 Main, where craft cocktails and local brews meet a welcoming atmosphere.

Nestled in the vibrant Downtown Durham, 106 Main is a lively bar that encapsulates the essence of the local nightlife with its inviting atmosphere, craft beverages, and a sense of community. Perfect for tourists looking to unwind after a day of exploring, this bar offers an eclectic mix of drinks and a friendly vibe.

A brief summary to 106 Main

  • Monday 4 pm-12 am
  • Tuesday 4 pm-12 am
  • Wednesday 4 pm-12 am
  • Thursday 4 pm-12 am
  • Friday 4 pm-2 am
  • Saturday 4 pm-2 am
  • Sunday 12 pm-12 am
Eve
From Eve

Know before you go

Hi, I'm Eve. Here are a few practical things to know before exploring 106 Main.

  • Visit during happy hour for the best drink specials, typically available from 4 PM to 6 PM.
  • Check their social media for live music events and special promotions.
  • Arrive early on weekends to secure a good spot, as it can get quite crowded.
  • Try the local craft beers for a true taste of Durham.

Do you manage this location?

Take control to get all the benefits, like improved information, better appearance, and stronger visibility across AI-powered discovery. Learn more about listing your business on Evendo

Activate your presence

Other nearby places you may find interesting

The closest places of the same kind, if this one is not quite what you had in mind.

Explore 106 Main on the Map

A handpicked selection of must-see spots near 106 Main, mapped for you.

Unlock the Best of 106 Main

Buy tickets

  • No tickets available

Book tours with entry

  • No tours available

Book tours without entry

  • No tours available

Discover more about 106 Main

Located in the bustling heart of Downtown Durham, 106 Main stands as a beloved bar that offers a unique blend of craft cocktails and local brews, making it a favorite among both locals and tourists. The vibrant atmosphere is enhanced by a warm and welcoming staff, ensuring that every visitor feels right at home. With its stylish decor and comfortable seating, it provides an ideal setting for both intimate gatherings and lively nights out with friends. The bar features an extensive drink menu that showcases a variety of options, from classic cocktails to innovative creations that highlight local ingredients. Whether you’re in the mood for a refreshing beer, a meticulously crafted cocktail, or a glass of fine wine, 106 Main has something to satisfy every palate. Additionally, the bar often hosts events and live music, adding to its dynamic ambiance and offering guests an opportunity to experience the local culture. Open late into the night, 106 Main is the perfect pit stop after a day of exploring Durham’s historic streets or enjoying its culinary delights. With its inexpensive prices and lively vibe, this bar is not just a place to grab a drink; it’s a quintessential part of the Durham experience that shouldn’t be missed.
Mobile App

Your all‑in‑one travel companion app

Explore expert travel guides, compare and book tours, experiences, hotels, and more—all from the palm of your hand. Download now for seamless trip planning wherever your wanderlust takes you.



Explore More of Research Triangle

Looking beyond 106 Main? Discover Research Triangle for broader travel guides, local hot-spots, and regional highlights.

Explore Research Triangle

Select Currency