Science and Industry Bar at Cane & Grain, Manchester
Sophisticated cocktails and a stylish vibe await you at Science and Industry, the first-floor bar of Cane & Grain in Manchester’s Northern Quarter.
Science and Industry is a stylish bar located on the first floor of Cane & Grain in Manchester’s Northern Quarter. Known for its sophisticated cocktails and unique atmosphere, it offers a distinct experience separate from the ground-floor Rib Joint and the third-floor Liars Lounge. The bar features a cozy, intimate setting perfect for enjoying expertly crafted drinks in a lively yet relaxed environment.
A brief summary to Science And Industry
- 49, 51 Thomas St, Manchester, M4 1NA, GB
- +441618397033
- Visit website
- Duration: 1 to 3 hours
- Mid ranged
-
Indoor
- Mobile reception: 5 out of 5
- Wednesday 6 pm-2 am
- Thursday 6 pm-2 am
- Friday 6 pm-3 am
- Saturday 2 pm-3 am
- Sunday 6 pm-2 am
Local tips
- Reserve a seat in advance to ensure access, as seating is limited and popular during peak times.
- Try the signature cocktails like the Old Fashioned Slushy for a unique drink experience.
- Combine your visit with dining at the Rib Joint on the ground floor for a complete Cane & Grain experience.
- Visit on weekends for extended hours and a livelier atmosphere.
For the on-the-go comforts that matter to you
- Restrooms
- Drink Options
- Food Options
- Seating Areas
- Information Boards
Science And Industry location weather suitability
-
Any Weather
Discover more about Science And Industry
A Distinctive Venue within Cane & Grain
Science and Industry serves as the first-floor bar in the multi-level Cane & Grain venue, situated at 49, 51 Thomas Street in Manchester’s vibrant Northern Quarter. This space contrasts with the Rib Joint on the ground floor, which focuses on hearty American-style food, and the Liars Lounge on the third floor, known for its energetic tiki parties. Science and Industry offers a more refined atmosphere, emphasizing quality cocktails and a curated drinking experience.Atmosphere and Design
The bar boasts a stylish, somewhat industrial aesthetic with a cozy ambiance that invites patrons to linger over drinks. Its design balances modern touches with rustic elements, creating an intimate yet lively setting. The venue’s decor includes unique features such as outlawed skateboards and eclectic art pieces, reflecting the Northern Quarter’s creative spirit. Seating is primarily for drinkers, enhancing the social and relaxed vibe.Cocktails and Drink Selection
Science and Industry is renowned for its sophisticated cocktail menu, crafted by expert bartenders who focus on quality and innovation. Signature drinks include classics with a twist and inventive concoctions like the Old Fashioned Slushy. The bar also offers a broad selection of beers, including local and international brews, catering to diverse tastes. This elevated drink experience distinguishes it from the more casual offerings on other floors.Food and Dining Experience
While the bar primarily focuses on drinks, some food options are available, though the menu is limited compared to the Rib Joint below. The food has received mixed feedback, with some patrons praising items like chicken burgers and poutine fries, while others note inconsistencies in availability and temperature. For a full dining experience, guests often combine their visit here with the ground-floor restaurant.Location and Local Vibe
Situated in Manchester’s Northern Quarter, Science and Industry benefits from the area’s reputation as a hub for creativity, nightlife, and independent venues. The bar fits well within this eclectic neighborhood, attracting a crowd that appreciates quality drinks in a stylish yet unpretentious environment. Its location on Thomas Street places it within easy reach of other cultural and entertainment spots.Visiting and Practical Information
The bar operates primarily in the evening, opening from 6 PM to 2 AM on most nights and extending to 3 AM on Fridays and Saturdays. It is a popular spot for those seeking a sophisticated night out with excellent cocktails and a distinctive atmosphere. Reservations are recommended, especially for seating, as the bar can be busy during peak hours.Iconic landmarks you can’t miss
Statue of the Duke of Wellington
0.3 km
A commanding Victorian bronze statue in Piccadilly Gardens honoring the Duke of Wellington’s military valor and political legacy.
Robert Owen Statue
0.4 km
Honoring Robert Owen, pioneer of social reform and the co-operative movement, through a striking statue in Manchester’s city heart.
The Undamaged Red Post Box
0.5 km
A resilient symbol of hope standing where devastation once reigned on Manchester's Corporation Street.
Murrays' Mill
0.6 km
Explore Murrays' Mills, the world’s oldest urban steam-powered cotton mill, where industrial heritage meets modern living in Manchester’s historic Ancoats district.
Arch of Chinatown
0.7 km
Europe's only imperial Chinese arch, a stunning gateway to Manchester's vibrant multicultural heart.
Connaught Building
0.7 km
Discover the historic Connaught Building in Manchester, a captivating landmark reflecting the city’s rich architectural heritage and vibrant urban spirit.
John Bright Statue
0.7 km
A marble tribute in Albert Square honoring John Bright’s legacy as a champion of free trade and social reform in Victorian Manchester.
Manchester City Council
0.7 km
Manchester City Council’s majestic Town Hall in Albert Square: a Victorian Neo-Gothic masterpiece and symbol of civic heritage.
Dalton Entry
0.8 km
Discover Dalton Entry, a hidden Manchester alley honoring John Dalton’s atomic theory and scientific legacy through art and history.
Albert Memorial
0.8 km
A grand Victorian Gothic monument in Albert Square celebrating Prince Albert’s legacy through art, science, and culture.
Victory Over Blindness
0.8 km
A powerful bronze memorial at Manchester Piccadilly honoring WWI veterans blinded in battle, symbolizing resilience and solidarity at eye level.
Mulberry Passage
0.8 km
Discover Mulberry Passage, a hidden Manchester alleyway celebrating John Dalton’s atomic theory through captivating art and historic charm.
St. Peter's Square
0.8 km
Manchester’s historic St Peter's Square blends rich heritage, iconic architecture, and vibrant urban life at the heart of the city centre.
Alan Turing Memorial
0.8 km
Explore the Alan Turing Memorial in Manchester, a tribute to the father of computer science and a symbol of resilience and innovation in history.
Manchester Central Library
0.8 km
Explore the architectural beauty and cultural richness of Manchester Central Library, a historic gem in the heart of the city.
Unmissable attractions to see
NQ Mural
0.1 km
Discover the vibrant NQ Mural, a colorful centerpiece of Manchester's Northern Quarter renowned for its dynamic street art and creative energy.
Manchester Craft and Design Centre
0.1 km
Discover handmade crafts, meet local artists, and enjoy artisan café culture in Manchester’s vibrant Northern Quarter.
Manchester Buddhist Centre
0.1 km
A serene urban sanctuary in Manchester’s Northern Quarter offering meditation, wellness, and a unique sober bar experience.
Breakout Manchester Church Street
0.1 km
Experience thrilling, immersive escape rooms on Manchester’s Church Street with diverse themes and challenging puzzles for all skill levels.
Shops
0.2 km
Discover Oldham Street, Manchester’s vibrant Northern Quarter hotspot for vintage fashion, indie shops, live music, and authentic urban culture.
DRY BAR
0.2 km
Discover the lively ambiance and eclectic music scene at DRY BAR, a premier bar and nightclub in Manchester's vibrant nightlife.
Afflecks
0.2 km
Explore Manchester’s legendary alternative indoor market, home to over 60 independent traders and a vibrant hub of creativity and culture.
Blue Rinse Manchester and Kilo Shop
0.2 km
Discover unique vintage fashion treasures by the kilo in Manchester’s vibrant Northern Quarter, blending style with sustainability.
Band on the Wall
0.2 km
Historic Manchester music venue famed for intimate gigs, jazz roots, punk legacy, and a unique stage high on the wall.
Stevenson Square
0.2 km
Manchester’s Stevenson Square: the energetic Northern Quarter hub for bars, culture, and vibrant nightlife in the city centre.
Express Building
0.3 km
A timeless Streamline Moderne masterpiece blending historic print heritage with vibrant modern workspaces in the heart of Ancoats, Manchester.
Greater Manchester Police Museum & Archives
0.3 km
Explore Manchester’s historic police station, original cells, and magistrates’ court in this immersive museum dedicated to policing heritage.
Manchester Arndale Shopping Centre
0.3 km
Manchester’s largest indoor shopping centre, with over 200 stores, restaurants, and leisure options in the heart of the city.
Piccadilly Gardens
0.3 km
Manchester’s central green space blending historic charm, modern design, and vital transport connections in a lively urban setting.
Empire Exchange
0.4 km
Dive into Manchester’s eclectic Empire Exchange, a treasure trove of vintage comics, vinyl, and collectibles where every visit uncovers a new story.
Essential places to dine
Cane & Grain
0.0 km
Discover Cane & Grain: where traditional American cuisine meets Manchester's vibrant nightlife scene in an unforgettable dining experience.
Almost Famous NQ
0.0 km
Bold, indulgent burgers and vibrant vibes in Manchester’s Northern Quarter, a must-visit for burger lovers and casual diners alike.
PUPA Restaurant & Bar
0.0 km
Authentic Mediterranean charcoal grill and vibrant atmosphere in Manchester’s Northern Quarter, perfect for steak lovers and lively dining.
Yard & Coop Manchester
0.1 km
Savor the best buttermilk fried chicken in Manchester’s Northern Quarter with bold flavors, craft beers, and a lively atmosphere.
63 Degrees
0.1 km
Experience meticulous French cuisine and elegant dining in Manchester’s vibrant Northern Quarter at 63 Degrees.
Liquor and Burn
0.1 km
Experience bold Mexican street food and vibrant cocktails in Manchester’s artistic Northern Quarter at Luck Lust Liquor & Burn.
TNQ - The Northern Quarter Restaurant & Bar
0.1 km
A beloved Northern Quarter gem serving seasonal British cuisine with award-winning roasts and warm, attentive service in a relaxed brasserie setting.
Evuna NQ
0.1 km
Experience authentic Spanish tapas and vibrant hospitality in Manchester’s Northern Quarter at Evuna NQ, a lively hub for food, wine, and culture.
Sicilian NQ - Restaurant and Bar
0.1 km
Authentic Sicilian cuisine and vibrant bar life in Manchester’s Northern Quarter, famed for arancini and inclusive vegan options.
Trof Northern Quarter
0.1 km
A multi-level Northern Quarter gem serving hearty British comfort food, craft beers, and rare bourbons in a lively, rustic setting.
Pieminister Manchester
0.1 km
Savor award-winning British pies in Manchester’s vibrant Northern Quarter, where tradition meets modern comfort food in a lively, welcoming setting.
Turtle Bay Manchester Northern Quarter
0.2 km
Experience vibrant Caribbean flavors and lively island vibes in Manchester’s Northern Quarter at Turtle Bay.
Tariff & Dale
0.4 km
Historic industrial charm meets modern British cuisine and inventive cocktails in Manchester’s vibrant Northern Quarter.
Riva Blu Italian Restaurant & Bar, Manchester
0.4 km
Contemporary Italian dining with cocktails in Manchester's vibrant Corn Exchange.
Viet Shack Restaurant
0.4 km
Experience bold Vietnamese street food flavors and vibrant fusion dishes in the heart of Manchester’s creative Ancoats district.
Markets, malls and hidden boutiques
Deadstock General Store
0.0 km
Discover useful beauty at Deadstock General Store, where Liam Jackson curates high-end Japanese designs, artisan gifts, and tailoring in Manchester's Northern Quarter.
&made
0.1 km
Discover unique handmade gifts and artworks at &made, a creative studio in Manchester’s vibrant Northern Quarter craft hub.
Jessica6 Designs
0.1 km
Discover unique luxury gifts and local artistry at Jessica6 Designs within Manchester’s vibrant Craft & Design Centre.
Studio One - Jewellery, Craft, Gifts and Homewares
0.1 km
Discover exquisite handmade jewellery and crafts at Studio One, a vibrant artisan studio within Manchester’s historic Craft and Design Centre.
Laissez Faire UK Fairtrade & Eco Clothes & Gifts
0.1 km
Discover fairtrade and eco-friendly fashion and gifts in the heart of Manchester’s vibrant Church Street district.
Cow Vintage Manchester
0.1 km
Discover trend-led vintage fashion and sustainable style in Manchester’s creative Northern Quarter at Cow Vintage.
Pop Boutique
0.2 km
Tucked into Oldham Street, Pop Boutique is Manchester’s well-curated vintage emporium for mid-century to 1990s fashion finds and eclectic accessories.
Red and Blue Umbrella
0.2 km
Discover timeless style and friendly service at Manchester’s Red and Blue Umbrella vintage clothing shop on Church Street.
Thunder Egg
0.2 km
Dive into a rainbow of quirky fashion and gifts at Thunder Egg, Manchester's colorful boutique for unique vintage-inspired styles and playful outfits.
Kiku Boutique
0.2 km
Bespoke corsets and vintage lingerie in Manchester's Northern Quarter: handmade elegance that defies fast fashion.
Nordic Muse Lifestyle Store
0.2 km
A quietly curated Northern Quarter boutique for simple, well-crafted jewellery and Nordic-inspired homeware.
Suzylovesmilo concept store
0.2 km
Discover unique vintage fashion and sustainable style at Suzylovesmilo, Manchester’s curated concept store blending Japanese influences with local creativity.
Amazonas Gifts
0.2 km
Discover unique gifts and souvenirs at Amazonas Gifts, nestled in the heart of Manchester Markets Piccadilly.
The Manchester Shop
0.2 km
Discover Manchester's soul in bee motifs, music tees, and proud souvenirs at this Northern Quarter gem within Afflecks Arcade.
Hoot
0.2 km
Discover magical gifts and Harry Potter treasures at Hoot, a charming boutique nestled in Manchester Arndale’s vibrant shopping heart.
Essential bars & hidden hideouts
Science And Industry
0.0 km
Sophisticated cocktails and a stylish vibe await you at Science and Industry, the first-floor bar of Cane & Grain in Manchester’s Northern Quarter.
Wolf at the Door
0.1 km
A vibrant Northern Quarter bar serving innovative tapas-style bao buns, craft cocktails, and a lively urban atmosphere.
The Daisy
0.1 km
Parisian subterranean cocktail haven in Manchester's Northern Quarter: eclectic vibes, masterful drinks, and weekend DJ magic beneath Evelyn's.
Behind Closed Doors
0.1 km
Descend into debauched delight at this Northern Quarter speakeasy, where retro telephones summon saucy cocktails amid erotic art, neon booths, and funky DJ beats until 4am.
Wilson's Social
0.2 km
All-day Northern Quarter hub: brunch by day, cocktails and beats by night in a multi-level party palace with pool, courtyard, and private den.
Night & Day Cafe
0.2 km
Manchester's intimate live music heartbeat in the Northern Quarter—where legends launched and nights ignite with raw indie energy.
NQ64 Northern Quarter
0.2 km
Retro arcade bar blasting 80s-90s nostalgia with neon cocktails, token games, and basement buzz in Manchester's Northern Quarter.
Mean Eyed Cat Bar Manchester
0.2 km
Dive into Manchester’s Northern Quarter for rebellious rock ’n’ roll vibes, free pizza, and legendary dice games at Mean Eyed Cat Bar.
Dusk Til Pawn
0.2 km
Secretive pawn-shop façade, intimate speakeasy interior and a menu of inventive cocktails in Manchester’s Northern Quarter.
The Washhouse
0.2 km
Step through a washing machine door into Manchester’s secret speakeasy, where inventive cocktails and quirky charm create an unforgettable night out.
Flok
0.2 km
Lively pub with excellent drinks and friendly vibes in the heart of Manchester’s Northern Quarter nightlife.
7Sins, Northern Quarter
0.2 km
A vibrant basement bar and gaming hub in Manchester’s Northern Quarter, mixing cocktails, pool, arcade games, and dance club energy.
Bar Fringe
0.2 km
A cozy Northern Quarter bar with quirky charm, top Belgian beers, live music, and a welcoming vibe for relaxed socializing.
The Fitzgerald
0.3 km
Velvet seats, craft cocktails and live jazz in a 1920s‑inspired Manchester speakeasy with a stage for cabaret and private hire.
The Crown & Kettle
0.3 km
Grade II-listed Ancoats gem with a world-class tin ceiling, craft beer mastery, and cozy Victorian vibes—Manchester's perfect pub hybrid.
For the vibe & atmosphere seeker
- Lively
- Relaxing
- Unique
- Casual
For the design and aesthetic lover
- Industrial Designs
- Modern Designs
For the architecture buff
- Landmarks
- Art & Design
For the social media creator & influencer
- Instagrammable
- Photo Spots
- Aesthetic Corners
For the eco-conscious traveler
- Public-Transport Accessible
For the kind of experience you’re after
- Cultural Heritage
- Photowalk
- Nightlife
For how adventurous you want the journey to be
- Easy Access
Location Audience
- Adult Friendly
- Couple Friendly
- Solo Friendly
- LGBT Friendly
