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Main Street Bed & Breakfast: A Historic Hannibal Retreat

4.8 (76)

Stay in a historic 1875 bank building in the heart of Hannibal, MO, steps from Mark Twain's legacy and the Mississippi Riverfront.

Experience the charm of Hannibal at the Main Street Bed & Breakfast, housed in a renovated 1875 bank building. Enjoy uniquely themed rooms, modern amenities, and a location steps away from Mark Twain's legacy and the Mississippi River.

A brief summary to Main Street Bed & Breakfast

Local tips

  • Book directly with the B&B for the best rates and personalized service.
  • Request a room with a jetted tub for a relaxing soak after a day of exploring.
  • Take advantage of the B&B's central location and walk to nearby attractions, restaurants, and shops.
  • Enjoy the complimentary continental breakfast, snacks, and beverages provided.
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Getting There

  • Walking

    From the Mark Twain Boyhood Home and Museum, walk north on Main Street for about 2 minutes (0.1 miles). The Main Street Bed & Breakfast will be on your left, across from The Brick Oven Italian restaurant. No costs involved.

  • Public Transport

    From the Hannibal bus station at 4811 McMasters Ave, take the OATS Transit in-town service. The ride to downtown Hannibal will cost $2.00. Get off near Main Street and walk a short distance to 201 N Main St. Call 660-415-0901 to schedule a ride.

  • Taxi

    From the Hannibal Regional Airport, a taxi ride to Main Street Bed & Breakfast will cost approximately $20-$25. The ride is about 15 minutes, depending on traffic. Taxi services are available at the airport.

Discover more about Main Street Bed & Breakfast

Nestled in the heart of Hannibal's historic downtown, the Main Street Bed & Breakfast offers a unique and intimate lodging experience. Housed in a renovated bank building dating back to 1875, this B&B features three uniquely themed guest rooms, each with private bathrooms, jetted tubs, and separate showers. Choose from the Arts and Crafts Suite, the Renaissance Suite, or the Safari Suite for a memorable stay.The Main Street Bed & Breakfast is ideally located for exploring Hannibal's top attractions. Just steps away, you'll find the Mark Twain Boyhood Home and Museum, Planters Barn Theater, and the Mississippi Riverfront. Enjoy a leisurely stroll along Main Street, browsing the charming shops, restaurants, and entertainment venues.Owners Michael and Pam Ginsberg, originally from Denver, Colorado, relocated to Hannibal in 1988 and remodeled the old F&M Bank building in 2000. They created a welcoming space for guests, combining historic charm with modern amenities. Mark Twain himself visited this building in 1903, adding to its historical significance.

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File:Mark Twain Boyhood Home 1.jpg - Wikimedia Commons

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