Best Nightclubs in Eastern Panama

10 nightclubs

1. 
   01
   Disco club4.3★1,395 reviews

   Casa Jaguar

   Casa Jaguar is a premier disco club and restaurant in Panama City, offering an electrifying atmosphere, delicious food, and unforgettable music for an exciting night out.

   289 min drive · 144 km·Av. Central España, Panamá, Provincia de Panamá

   Show on map Casa Jaguar
2. 
   02
   Disco club4.2★1,152 reviews

   Chill out discotheque

   Experience the vibrant nightlife at Chill Out Discotheque, a premier disco club in Panama City. Enjoy pulsating music, energetic dance floors, and an unforgettable atmosphere that promises an exciting night out.

   Thu–Sat 22:00–4:00 · Sun 14:00–22:00

   285 min drive · 143 km·Causeway de Amador, Plaza Figali, proyecto Zona de la Rumba, Panamá

   Show on map Chill out discotheque
3. 
   03
   Disco club4.4★215 reviews

   Moloko Plus

   Moloko Plus is a lively disco club in Panama City, renowned for its electrifying atmosphere and diverse music. It’s a must-visit for tourists seeking an unforgettable night out in the heart of the city.

   288 min drive · 144 km·C. 12 Oeste 7B, Panamá, Provincia de Panamá

   Show on map Moloko Plus
4. 
   04
   Bar4.2★180 reviews

   La Tana

   Experience the vibrant nightlife at La Tana, a lively bar and nightclub in the heart of Panama City, known for its great music, energetic atmosphere, and friendly service. Perfect for dancing the night away!

   Tue–Wed 17:00–2:00 · Thu–Sat 17:00–4:00

   289 min drive · 144 km·Calle 12 B, Panama City, Panamá Province

   Show on map La Tana
5. 
   05
   Event venue4.4★122 reviews

   La Nueva Gruta Azul

   La Nueva Gruta Azul is a lively event venue in Panama City, known for its vibrant atmosphere, diverse events, and welcoming ambiance, perfect for tourists seeking local culture and entertainment.

   Mon–Sat 12:00–3:00

   300 min drive · 150 km·C. Tercera Rio Abajo, Panamá, Provincia de Panamá

   Show on map La Nueva Gruta Azul
6. 
   06
   Adult entertainment club4.0★140 reviews

   Le Palace

   Le Palace in Panama City is an exciting adult entertainment club that promises an unforgettable nightlife experience filled with vibrant performances and a lively atmosphere. With its dedicated staff and welcoming environment, it's a popular spot for those looking to enjoy a night out in the city.

   Mon–Wed 20:30–3:00 · Thu–Sat 20:30–4:00

   293 min drive · 147 km·C. 52 Este, Panamá, Provincia de Panamá

   Show on map Le Palace
7. 
   07
   Night club3.9★97 reviews

   La Mayor Night Club

   La Mayor Night Club in Panama City is the ultimate nightlife destination, offering a dynamic atmosphere, exceptional music, and a chance to connect with fellow party enthusiasts. Dance the night away in this lively venue that truly embodies the spirit of Panama's nightlife.

   Open 24 hours

   289 min drive · 145 km·XF47+5CC, C. Pablo Arosemena, Panamá, Provincia de Panamá

   Show on map La Mayor Night Club
8. 
   08
   Night club3.8★55 reviews

   Envy club

   Located in the heart of Panama City, Envy Club is a popular night spot that offers an electrifying atmosphere, great drinks, and lively entertainment, perfect for both locals and tourists looking to enjoy the nightlife.

   293 min drive · 147 km·C. Aquilino de la Guardia 06, Panamá, Provincia de Panamá

   Show on map Envy club
9. 
   09
   Gay night club4.0★44 reviews

   XS Club

   Experience the vibrant energy of XS Club, a premier gay night club in Panama City that offers an unforgettable night out with electrifying music, lively performances, and a welcoming atmosphere that celebrates diversity.

   Wed 22:00–4:00 · Fri–Sat 22:00–4:00

   293 min drive · 146 km·Centro Comercial El Deposito, Av. Juan Pablo II, Panamá, Provincia de Panamá

   Show on map XS Club
10. 
    10
    Night club5.0★3 reviews

    El Huaso Night Club Panama Centro Calidonia

    El Huaso Night Club in Panama City offers an electrifying nightlife experience, blending local culture with vibrant music and dance to create an unforgettable evening for tourists and locals alike.

    289 min drive · 145 km·XF76+C3W, Panama City, Panamá Province

    Show on map El Huaso Night Club Panama Centro Calidonia